Deal Note #1 — An Idea Needs Evidence
Why a compelling scientific idea becomes investable only when evidence begins to reduce its most important risks.
Journal
A collection of articles and observations on early-stage life sciences, investing, and company building.
From the ChaosBio Deal Room
Lessons from reviewing early-stage life sciences companies. Company identities and confidential information are omitted to protect confidentiality.
Founder’s Playbook
Evergreen articles to help life science founders build investable companies.
Why You Need Angel Investors on Your Cap Table
Why the right angel investors can bring credibility, networks, expertise, and support beyond the initial check.
What Makes Me Pause in an AI Healthcare Pitch
Five questions I ask to separate genuine healthcare innovation from AI hype.
Why Great Science Doesn’t Always Become a Great Company
Strong science is essential, but investors ultimately evaluate risk, execution, and the path to a successful exit.
What Angels See as Red Flags
Common red flags investors notice in life sciences pitches—and how founders can avoid them.
If You Are a First-Time Founder, You Need a Team
How cofounders, advisors, and early hires make first-time founders more fundable and more likely to succeed.
What I Look for in a Pitch Deck
Six things an investor notices when a life sciences pitch deck lands in their inbox.
Investment Perspectives
Commentary on biotech, venture investing, innovation, and the life sciences ecosystem.
Investment Perspective
Coming soon.